There are some good layout tips/guidelines spread over various threads here - a few I found useful -
https://www.diyaudio.com/community/...compared-to-wire-cross-sectional-area.393115/
https://www.diyaudio.com/community/threads/any-tips-for-routing-heaters-on-a-pcb.193366/
https://www.diyaudio.com/community/threads/pc-board-design-for-pse-amp.234474/
https://www.diyaudio.com/community/...compared-to-wire-cross-sectional-area.393115/
https://www.diyaudio.com/community/threads/any-tips-for-routing-heaters-on-a-pcb.193366/
https://www.diyaudio.com/community/threads/pc-board-design-for-pse-amp.234474/
I have designed numerous valve amps using PCB and not had any problems.
A little care is needed with HV, input circuit and hum.