The UK has the 2nd or 3rd largest population of overseas Chinese in Europe.
The other countries in the top 3 are France and Russia.
My daughter is currently doing her Master in Maths and over half the students on her course are Chinese who just came back from China after the winter holidays.
Italy's average age is 6 months lower than that of Germany.
I think Italy's situation is unfortunate coincidence.
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FWIW, I’m 68 and did have chicken-pox as a kid, as did my wife. Upon our GP’s advice we both had the Shingles vax last year, 2 shots, 6 months apart in our case. They were able to be administered by our local pharmacist, and neither of us experienced any of the side effects that he noted some folks do - just a couple days of mild firm swelling less annoying than bee stings or mosquito bites I’ve had. So hopefully we’re covered for a while.
Interestingly enough though, the same doctor in whom I otherwise placed much confidence has advised for years against the annual flu shots, and I can’t count on a single hand the number of years during the past several decades that I didn’t experience a mild to moderately inconvenient annual “winter cold”.
But, while I got the side-eye from my wife every time I suggested we second guess that particular advice, it might be time to reconsider?
We in Canada love to humble brag about our healthcare system, but it is not without its flaws, highest among them by my own reckoning being the asinine model of paying family doctors for their services. As a matter of fact just this week I received a boilerplate form letter from my GP advising that due to overwhelming workloads that the ever depleting number of general practitioners can handle, name was one randomly selected to be deleted from her practice, and that I’ll need to pay a third party records company to have access to a digital copy of my 50yrs of medical records, and that while they’re able to put my name on a consultation wait list, I’m otherwise on my own to find a permanent replacement.
What’s most ironic about this particular situation is that my current GP is one of two siblings who just recently took over their father’s practice. He had been our GP for at least 40years, and had delivered both our now adult children.
Interestingly enough though, the same doctor in whom I otherwise placed much confidence has advised for years against the annual flu shots, and I can’t count on a single hand the number of years during the past several decades that I didn’t experience a mild to moderately inconvenient annual “winter cold”.
But, while I got the side-eye from my wife every time I suggested we second guess that particular advice, it might be time to reconsider?
We in Canada love to humble brag about our healthcare system, but it is not without its flaws, highest among them by my own reckoning being the asinine model of paying family doctors for their services. As a matter of fact just this week I received a boilerplate form letter from my GP advising that due to overwhelming workloads that the ever depleting number of general practitioners can handle, name was one randomly selected to be deleted from her practice, and that I’ll need to pay a third party records company to have access to a digital copy of my 50yrs of medical records, and that while they’re able to put my name on a consultation wait list, I’m otherwise on my own to find a permanent replacement.
What’s most ironic about this particular situation is that my current GP is one of two siblings who just recently took over their father’s practice. He had been our GP for at least 40years, and had delivered both our now adult children.
rayma -- I'm not sure what your question is alluding to, but does this document answer it? People 65 Years and Older & Influenza | CDC (flu shot vs nasal spray)
Charles --
Italy Age structure:
0-14 years: 13.6% (male 4,326,862 /female 4,136,562)
15-24 years: 9.61% (male 2,994,651 /female 2,984,172)
25-54 years: 41.82% (male 12,845,442 /female 13,183,240)
55-64 years: 13.29% (male 4,012,640 /female 4,261,956)
65 years and over: 21.69% (male 5,817,819 /female 7,683,330) (2018 est.)
United Kingdom Age structure:
0-14 years: 17.59% (male 5,871,268 /female 5,582,107)
15-24 years: 11.71% (male 3,895,850 /female 3,726,311)
25-54 years: 40.29% (male 13,387,119 /female 12,843,549)
55-64 years: 12.22% (male 3,936,466 /female 4,022,245)
65 years and over: 18.19% (male 5,321,392 /female 6,518,939) (2018 est.)
Germany Age structure:
0-14 years: 12.83% (male 5,299,798 /female 5,024,184)
15-24 years: 9.98% (male 4,092,901 /female 3,933,997)
25-54 years: 39.87% (male 16,181,931 /female 15,896,528)
55-64 years: 14.96% (male 5,989,111 /female 6,047,449)
65 years and over: 22.36% (male 7,930,590 /female 10,061,248) (2018 est.)
Source: United Kingdom Age structure - Demographics (and respective Italy, Germany sites)
Yes, Germany and Italy are similar age demographically and other circumstances will highlight why one got hammered and one hasn't (yet). But both are poised to be hurting, given both (and Japan) are in the top-5 median age per country.
Charles --
Italy Age structure:
0-14 years: 13.6% (male 4,326,862 /female 4,136,562)
15-24 years: 9.61% (male 2,994,651 /female 2,984,172)
25-54 years: 41.82% (male 12,845,442 /female 13,183,240)
55-64 years: 13.29% (male 4,012,640 /female 4,261,956)
65 years and over: 21.69% (male 5,817,819 /female 7,683,330) (2018 est.)
United Kingdom Age structure:
0-14 years: 17.59% (male 5,871,268 /female 5,582,107)
15-24 years: 11.71% (male 3,895,850 /female 3,726,311)
25-54 years: 40.29% (male 13,387,119 /female 12,843,549)
55-64 years: 12.22% (male 3,936,466 /female 4,022,245)
65 years and over: 18.19% (male 5,321,392 /female 6,518,939) (2018 est.)
Germany Age structure:
0-14 years: 12.83% (male 5,299,798 /female 5,024,184)
15-24 years: 9.98% (male 4,092,901 /female 3,933,997)
25-54 years: 39.87% (male 16,181,931 /female 15,896,528)
55-64 years: 14.96% (male 5,989,111 /female 6,047,449)
65 years and over: 22.36% (male 7,930,590 /female 10,061,248) (2018 est.)
Source: United Kingdom Age structure - Demographics (and respective Italy, Germany sites)
Yes, Germany and Italy are similar age demographically and other circumstances will highlight why one got hammered and one hasn't (yet). But both are poised to be hurting, given both (and Japan) are in the top-5 median age per country.
Yesterday Germany had 2 deaths out of over 1200 confirmed cases.
The UK had 6 out of just under 400.
The UK had 6 out of just under 400.
What's your point? Low N statistics are unreliable? Difference of care and distribution of comorbidities among the population? Population interaction dynamics?
Got it. I thought you were hinting at some hypothesis, but not sharing (and I wasn't picking it up)
As to why Germany's death rate is so low -- neither do I, but I'll admit I haven't gone looking for plausible reasons. First order guess is it hasn't seen spread to high risk populations yet, especially coupled with lead time. (If one looks at the Kaplan Meier curves)
As to why Germany's death rate is so low -- neither do I, but I'll admit I haven't gone looking for plausible reasons. First order guess is it hasn't seen spread to high risk populations yet, especially coupled with lead time. (If one looks at the Kaplan Meier curves)
Usefull thread, thank you so much.
My grand-mother used to vaccine against flu every year and very early : each time she had flu symptoms after. A taunt of me died after a flu vaccin in a retirment place.
What happend, were she already ill, did the flu virus slighty different ? Does the quantity of vax too big for old people (protocol?) ?
There is also polemics about the time needed to wash ones hands. Should it be more than 1 minute for instance ? Nails to be cut short, etc ?
I also see incredible things : people washings glass doors and door handles from building with a same tissus not using air spray
Do they not make virus to travel easilier and faster ? Soe also guessing about air humidity and closed air cooling system in buildings as there were some lung diseases already due to a microb or virus ties ago ??A last one, do we know the lasting of CV-19 on an inert material (food, glass, cotton and so on) ?
Sorry if already asked.
BTW on the history side about medecine culture, I have found this story amazing : Ignaz Semmelweis - Wikipedia
Also the treatment regimens are extremely varied. In the US, seems like you get nothing unless you’re lucky enough to be able to sign up for Remdesivir or your doctor is feeling adventurous. In South Korea they are supposedly giving out hydroxychloroquine to some patients. In China they were giving many patients lopinavir / ritonavir and steroids for severe cases.
Oh wow, you guys actually know treatments. When my daughter was in the hospital for respiratory problems, they at first pursued giving her asthma medications, including Ventolin and others whose names I don't remember. They gave her so much that she had the shakes for many hours later. It was only after these had no effect that they gave her an x ray and diagnosed pneumonia. I'm wondering if this is what they normally would have done, or was infuenced by the Covid 19 outbreak?
Emergent epidemics (pandemic too early?) are really the wild west. It's essentially being caught with one's pants down, with the acknowledgment that it's impossible to not be completely caught off guard by these circumstances. If we could plan for a disease jumping species then things might be different, but I expect my tricoder before then...
I think Gilead is clamping down (or FDA or insurance providers are? Dunno, haven't heard of it being shady for what it's worth) on Remdesivir?
I think Gilead is clamping down (or FDA or insurance providers are? Dunno, haven't heard of it being shady for what it's worth) on Remdesivir?
So seems like some of you know your stuff about this topic. I'm diabetic, type 1 and earlier in Oct. I received my flu and also Pneumonia vaccine. If I were to catch Covid-19 would the pneumonia shot protect from getting the pneumonia which seems like what is killing most??
Usually the adjuvantiae are listed for the various vaccines.
Which type depends on the specific vaccine, sometimes it is aluminiumhydroxid, other are combinations of squalen-in-water and others (can be for example purified parts of bacteriae).
Rationale is indeed, as you've mentioned, that less of the original virus-proteins is needed to get the response from the immune system.
Your pneumonia vaccine will protect against Streptococcus pneumoniae. Pneumonia is an infection of the lungs so it's a wider catch-all term, as one can have viral pneumonia (Covid-19 would fall in this bin), fungal pneumonia, bacterial pneumonia (which your vaccine is designed to mitigate, at least the most prevalent and dangerous strain)
Just on BBC news they spoke to an Italian doctor who said that the high death rate in Italy (8%) is due o the fact that they are not able to give everybody oxygen who needs it.
Their excellent health service has simply been overwhelmed.
Their excellent health service has simply been overwhelmed.
Yes, Italy has had another 200 deaths today just about.
An interesting discussion with some data:
An exhaustive lit search shows that only 5/85 SARS patients and 150/1397 COVID-19 patients were smokers, far below the 27% active smokers in china. Can anyone find a study that was missed? : COVID19
It appears smoking may actually protect against infection with SARS. Not conclusive, but interesting.
An interesting discussion with some data:
An exhaustive lit search shows that only 5/85 SARS patients and 150/1397 COVID-19 patients were smokers, far below the 27% active smokers in china. Can anyone find a study that was missed? : COVID19
It appears smoking may actually protect against infection with SARS. Not conclusive, but interesting.
I think a number of patients were offered it via Expanded Access waiver but now that the spread is wide, supply limited, and Phase 3 trials are ongoing you’ll probably have to get into a trial to receive it.
No idea, as a layperson I didn’t even think the combination would work on this virus at all despite some of the receptor binding domain being similar to HIV apparently. My uninformed understanding is that the ritonavir is at least partially used for the CYP3A4 inhibition.
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