The Biology and Immunology Corner

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And how fast was the onset of the illness (respectively)? Did one catch it then everyone else follow suit shortly thereafter? Fast onset and everyone getting sick after the first person is clearly sick points away (but not definitively) from COVID-19 and towards the flu.

Wishing you and your family the best KaffiMann

Thank you.

There's been a distinct delay between getting initial symptoms, and a period of 5-7 days of seemingly innocent sniffling (so the virus gets spread around easily), before the onset of more profound feeling of sickness for about 2-4 days, then fever 3-5 days, another 3-5 days until you start feeling 100%. I have no idea of where or when I might have gotten it to begin with.
Dry cough for everyone, the youngest has very heavy dry cough even all through the nights, except for my oldest daughter. She's had some allergy issues and we immediately started giving her the inhalator medicine. Despite that she had super heavy breathing through the worst of it.

Again, I know there's no way to say for sure if this is it or not. But whatever it is, does not feel like the flu, almost like the cold except the onset period and strong tiredness when it's full-on, much heavier fever for a relatively long duration.

I joke it off somewhat, but it's not been very nice at home for a while now.

Edit:
I'm feeling pretty okay now, but walking around in some shops some people are wandering around sniffling and sneezing openly, seemingly without any regard to the situation.
People feel absolutely fine through the beginning, just a little bit runny.

Edit2:
I suspect whatever I got, I was originally infected ca around week 7 or 8 some time, but I cannot really say for sure.
 
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I'm in the at risk class (68) and I'm meeting with my Father (92 w/ Parkinson's) often so I have a very immediate concern for facts, rather than promises.

Demian, the immediate best reaction would probably be to stop seeing your father frequently for the time being. Lower the possibility of either infecting the other.

Belgium just announced all restaurants and bars closed for the next three weeks. Stopping the spreading is very effective.

I find it curious that the US has stopped flights from the Schengen countries but has no qualms from infected people from hotspots like Seattle to fly anywhere in the country. But I do realize there is most likely a political dimension to this which I won't go into.

Jan
 
Again, I know there's no way to say for sure if this is it or not. But whatever it is, does not feel like the flu, almost like the cold except the onset period and strong tiredness when it's full-on, much heavier fever for a relatively long duration.

I wish you the best

George
 

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I'm just troubled by the fact that I am a member of the 'elderly population' which is most at risk.

At which point should I start to panic (or reach for the toilet roll)? 🙁

My company considered me in the same risk group, so they just asked me to stay home (normal salary included). Looks like, here in Denmark companies take the responsibility regarding their employees seriously.
 
I find it curious that the US has stopped flights from the Schengen countries but has no qualms from infected people from hotspots like Seattle to fly anywhere in the country. But I do realize there is most likely a political dimension to this which I won't go into.

Jan

Yeah Jan, neither would I, except point out the strangest behaviour from DT, banning "incoming from the whole of EU.... except UK???
Maybe a stupid reward for leaving the union 🙂 🙂 🙂

Kaffiman.... Sorry to hear about your troubles.
Wish you a speedy recovery 🙂
 
Just want to add that the "sniffling" phase was so light, I didn't even think about it until the kids started. Think it could be why so many get sick, it feels like nothing at all. When the fever started it could be seen as more or less a minor side effect. Really hope I've had it so we can stop thinking about another round...
 
Indeed, it's not political to say some are more responsible than others.

There are countries whom freezed real estates mortgages, enterprises taxation, incomes taxations to help the shops, little enterprises, some others injected monney to stand them.

It's just life is more important that monney. People should stop to see political plot everywhere each time a country is named. As it's not populism to say some think more growth point and elections than public health care. It's an evidence to say that's pandemic everywhere as airports are inside countries, so responsible to say to local areas to manage the viral cluster hot spots and citizen duty for everyone to help local authorities.

No need to panic and full up the basement with food, it's cunterproductive. Supply chain for food will not be stopped, it's not atomic radiation... it asks just duty attitude, benevolence and a lot of informations to fight myths, help the less knowledged people as I and people that needs real emmergency care. I can't believe biggest organisations are not freezing stock exchanges that are rulled by stupids algorythms to help their citizen and enterprises...and banks to stop to ask some countries and people to give back the monney of mortgages now... just freeze it for some weeks Do they not learn from 2008 ?

Stupidiry has no frontier and you will always see two sapiens figthing for toilett paper in a supermarket and taxman saying mines are not dangerous for the health. Hapilly most people are serious and responsible.
 
Dr Francis Boyle is saying Cov-19 is engineered.


Max.






Conspiracy theory again???
Is it so hard to believe, that nature just pops up something unknown once and an while, concidering how we treat the planet???
What about Ebola, the flu, black plague just to name a few???
The plague for one was way back before anyone even knew/had the tools to engineer anything 🙁
 
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Dr Francis Boyle is saying Cov-19 is engineered.


Max.


And I say that based on the same studies, Cov-19 comes from the Martians that visit us regularly.

I made a search for the studies that Dr. Francis A. Boyle used in this conspiracy-theory video.
Read them yourself and give us a third opinion. After all, neither Dr. (Law professor) Francis A. Boyle nor me are Physicians, Biologists and such. I hope you are.

Study: The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade - ScienceDirect

Study: SARS-like cluster of circulating bat coronavirus pose threat for human emergence
SARS-like cluster of circulating bat coronavirus pose threat for human emergence

Study: Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry
Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer variable susceptibility to SARS-CoV entry | SpringerLink

Study: The possible origins of 2019-nCoV coronavirus
(PDF) The possible origins of 2019-nCoV coronavirus

Study: Clinical characteristics of 2019 novel coronavirus infection in China
https://www.medrxiv.org/content/10.1101/2020.02.06.20020974v1.full.pdf

George
 
In the US there are hot issues about getting tested. I have seen nothing about he accuracy of the tests. I doubt they are 100%. is there any info on percentages of false positives/negatives? And how does any entity gear up to make 1 million tests in a week? That's a gargantuan task for almost any product, let alone one that did not exist a few month ago.
California's governor also explained that while having the tests is good the necessary reagents were in short supply. Can anyone provide more info/background?

I'm in the at risk class (68) and I'm meeting with my Father (92 w/ Parkinson's) often so I have a very immediate concern for facts, rather than promisses.

The "tests" are RT-PCR assays. Basically, we use HIV-1 reverse transcriptase to make a DNA copy of the virus RNA genome. Then use regular PCR (polymerase chain reaction) to make lots a lots of the same DNA. If we see a positive signal, that means that the virus RNA was there in the first place and was well "amplified".

RT-PCR is an EXTREMELY sensitive assay. False positives and negatives are very unlikely unless the assay itself is performed poorly or non-sterile. That said, with the current panic and rush on tests, that last part is awfully important! I know for a fact that the first run of tests (several hundred thousand) were messed up as the kits' negative controls were contaminated with the kits' positive control. So all the controls came back positive. The "fix" was just to use water from the lab instead of the boxed control. Worked fine; but it's worth understanding.

The best thing to do would be to limit contact as much as possible; as annoying and inconvenient that may be. The best defense against a pathogen like this is isolation and sanitization.

PS. Sorry for not posting as often. Things have gotten a bit out of hand here as my campus is half clinical/medical, half research. If I have missed good question, please, anyone, point them out to me and I'll answer to the best of my ability.
 
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