The Biology and Immunology Corner

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What I'd like to know is if it's effective to "health up" as much as possible, prior to taking on this viral infection.

I would think some cardio /respiratory capability might go some way to fending off this one, compared to "sedentary" with a "smoking" complication.

Personally, I've been trying to run. Jog, actually. 4 years ago I was running 7ks, but last year, after an RP operation, that fell to about a mile, as I did and do feel weakened after hospitalization.

Trying to get back to that level and taking liberty with a gentle progress, finding it comes back quickly. I'll build up endurance as best I can before it comes my way. Hopefully - at 63 - I'll survive it.

Honestly depending on how fast this disease spreads, it might be too late to gain the benefits of adaptation, and heavy exercise is an immuno-suppressant. Mild exercise doesn't seem to immunosuppress and healthing up, as you say, has manifold good outcomes. In summary, it's like the quote, “The best time to plant a tree was 20 years ago. The second best time is now.” If this provides the impetus, take it.
 
I took the data and related it to the size of the populations. There's new US datastream as the CDC is now using state health authorities. Someone care to guess where the US rate of infection might go.

The discontinuity in the data arises from no provincial reports at WHO for the period in which it is missing.

BTW, in Hubei Province 58% to 61% of doctors smoke, in Guandong it's 46%
 

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I took the data and related it to the size of the populations. There's new US datastream as the CDC is now using state health authorities. Someone care to guess where the US rate of infection might go.

The discontinuity in the data arises from no provincial reports at WHO for the period in which it is missing.

BTW, in Hubei Province 58% to 61% of doctors smoke, in Guandong it's 46%

I'm sorry but sometimes I have trouble understanding things that everyone else seems to get...
I have a couple of questions. What are the x and y axis? Could you tell me what the difference is between USA and USA new?
Thanks,
Glenn
 
Mayor Bill de Blasio raised the potential for a citywide quarantine similar to northern Italy’s lockdown amid the global coronavirus outbreak.
“It’s a possibility but I think people are getting a little ahead of ourselves and we should be careful,” the mayor said on CNN Monday.

Mass quarantine would flatten the curve and save many lives. I'd be surprised if the American government doesn't do that. I'm sure the American people would drop all differences and come together to do whatever was necessary. In much the same way they did after 9/11.
Time will tell...
 
State of emergency declared here in MA, apparently the presumed cases more than doubled in the past 24 hours.

The state has received permission to handle testing here at multiple labs, not sure about test kits. I heard something about 4000 test kits are available or about to be available.
 
Fun projects on hold, have been in a major medical center, basically living there.
The patient is a relative.

I've run into some pretty serious age discrimination last few days.
Security has been noticeably increased. Younger people (med staff - visitors) have more mobility I guess because not considered a risk.

Seems the media has done its job well.
But the fact that children never are really at risk is never broadcast.
 
Mayor Bill de Blasio raised the potential for a citywide quarantine similar to northern Italy’s lockdown amid the global coronavirus outbreak.
“It’s a possibility but I think people are getting a little ahead of ourselves and we should be careful,” the mayor said on CNN Monday.

Mass quarantine would flatten the curve and save many lives. I'd be surprised if the American government doesn't do that. I'm sure the American people would drop all differences and come together to do whatever was necessary. In much the same way they did after 9/11.
Time will tell...

It could happen, but I don't think it would be China-style. Nor would it be as effective as you would see many people ignore it.

The other concern is that you will just end up with a ton of cases once you end the quarantine. You've slowed the spread, but then air travel and daily life resumes and you get another surge in cases.
 
It could happen, but I don't think it would be China-style. Nor would it be as effective as you would see many people ignore it.

The other concern is that you will just end up with a ton of cases once you end the quarantine. You've slowed the spread, but then air travel and daily life resumes and you get another surge in cases.

I thought this may happen in China as they relax restrictions.

It will be interesting to see what happens in the coming weeks. Two weeks should tell.
 
I'm sorry but sometimes I have trouble understanding things that everyone else seems to get...
I have a couple of questions. What are the x and y axis? Could you tell me what the difference is between USA and USA new?
Thanks,
Glenn

The X-Axis is the date at which cases exceeded 40 -- so on Day 1 for the US the number of cases had jumped from 35 to 53. Day 1 for china was January 21.

The Y-Axis is the number of cases. New US data arises from a reporting change at the CDC. There are more state labs reporting into the CDC, but this isn't reflected in the WHO data. Worldometers seems to be on top of the data.

Cases are being resolved, binary!

The data is from World Health Organization, US CDC, United States Coronavirus: 975 Cases and 30 Deaths - Worldometer etc.

The fella in New Rochelle who was at the epicenter, had been at the AIPAC conference a few weeks ago and believes he contracted the disease there. He was also active in his temple which was a short walk from where he lived. He had been in 3 area hospitals for treatment of pneumonia and non of these had the negative pressure tents necessary for containment. He was also rode the train into NYC.

The Biogen conference in beantown resulted in 28 new cases.
 
The X-Axis is the date at which cases exceeded 40 -- so on Day 1 for the US the number of cases had jumped from 35 to 53. Day 1 for china was January 21.

The Y-Axis is the number of cases. New US data arises from a reporting change at the CDC. There are more state labs reporting into the CDC, but this isn't reflected in the WHO data. Worldometers seems to be on top of the data.

Cases are being resolved, binary!

The data is from World Health Organization, US CDC, United States Coronavirus: 975 Cases and 30 Deaths - Worldometer etc.

The fella in New Rochelle who was at the epicenter, had been at the AIPAC conference a few weeks ago and believes he contracted the disease there. He was also active in his temple which was a short walk from where he lived. He had been in 3 area hospitals for treatment of pneumonia and non of these had the negative pressure tents necessary for containment. He was also rode the train into NYC.

The Biogen conference in beantown resulted in 28 new cases.

The attack rate of this is amazing. It's not quite measles I'm sure, but still. I've never had influenza in my life to my knowledge, and I only started getting a shot last year. I'm confident if I spent 10 minutes in a room with someone infected with this I would get it.
 
It could happen, but I don't think it would be China-style. Nor would it be as effective as you would see many people ignore it.

The other concern is that you will just end up with a ton of cases once you end the quarantine. You've slowed the spread, but then air travel and daily life resumes and you get another surge in cases.

I imagine you're right about an uptick once the quarantine ends. I think that's ok though. I believe the major benefit of a quarantine would be to slow down the spread. That would give hospitals a chance to catch up with all the cases. The worst thing would be for the hospitals to become overwhelmed and not be able to take in any more new cases. Then you'd have people dying who would otherwise make it if they'd had access to health care...

I don't think any North American quarantine would be as effective as the Chinese one either...but even a less effective quarantine would be beneficial if it spread out the same number infections over a longer period of time. That would be a win.
 
WHO is saying somewhere in the 2-2.5 replication range. Obviously that has to be taken in context of population dynamics. Higher than influenza, but we are also a naive population, at least this year. Got nothing on colds, that's for sure, but you're not wrong. And the couple day window between shedding and presenting symptoms hurts isolation efforts.
 
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