Probably not. I keep a few cans of compressed air around for the occasional dusting. I have some of my raspberry Pi’s ‘naked’ , running piCore and moode , for years with no problem ( I know that I just now jinxed myself). I am counting on the other exposed components to be similarly immune to the occasional dust bunny. I like the exposed aspect of the set up. I can insert a new piece (pre-amp, amp etc.) as I’m building something and then I can easily test it for functionality etc. If not testing something new, it’s a great sounding platform for that listening space. Thanks for your question and interest!