What will happen if I do this?

The question with the A26, for example, is which sounds better at 500-2000 Hz? A 4" midrange driver or a 10" woofer or a 1" excel tweeter?

[500*2000]^0.5 = 1000 Hz power mean

~13543/pi/1000 = ~4.311" effective diameter, so with a ~94.2 cm^2 Sd, a 5.25" is a bit small and a 5.5" a tiny bit large, so 4" if your only small option.