• WARNING: Tube/Valve amplifiers use potentially LETHAL HIGH VOLTAGES.
    Building, troubleshooting and testing of these amplifiers should only be
    performed by someone who is thoroughly familiar with
    the safety precautions around high voltages.

The 6V6 Lacewood Amo V2.0

I have argued with folks on this forum before, them saying that my measured voltages and distortion numbers etc. "Are WRONG" because it doesn't match either their simulation or calculations from a tube data sheet. I can see using these tools as a starting point and then tweaking the real world built amp from there. I use the power supply sim software PSUD2 regularly. But it's a bad idea IMHO to rely solely on them or trust their results like it's a bible, and then dismiss the actual built results because it doesn't match a simulation of some calculations.

That goes against the whole idea of scientific testing, and honestly I am shocked how many classically trained engineers dismiss real world results when it doesn't match what they calculated/computer sim'd.
 
Simulation makes a lot of assumptions. Perfect tubes, sometimes people use perfect transformers (no DCR, leakage inductance etc), perfect voltage sources (no ripple, zero impedance). Even taking all of that into account when possible I have seen better, similar and worse distortion and power output results comparing simulations with real prototypes. DC operating points are pretty good though, provided you use a decent tube model.