The biggest “problem” is the 120 volt non-center-tapped secondary. If you’re building solid state, that limits you to a single 160-ish volt supply which means a very large capacitor coupled or even larger bridged amplifier. If that floats your boat, it will work fine. Smaller trafos work quite well to build tube amps, either running off 160 or so Volts or 320 with a doubler.
A 240 to 240CT (120-0-120) may be operated from 120 volts to give 60-0-60 or +/-84 V. You do not get full power rating, as you are limited by secondary current. You end up with a lot of magnetic headroom and it runs very quiet. I have several amps with these in them. While I would never pay full price for a transformer to be used this way, if you find one cheap it’s a good choice. A 1 to 2 KVA makes a nice 250W/ch amp.
I just bought two 110 to 480v 900VA EI core from Skycraft. Both slightly different but equally useable. Not your typical isolation transformer, but in the same general family. Makes 650 volt B+. Can run a lot of KT88s (or sweep tubes) with those.