Positioning Subwoofer

When subs (eg multiple, but applies either way) average over different locations it also irons out the response in those locations.

Yes, exactly. Though perhaps not very straightforward.
You'll get different results from different placements, it's even possible that some frequencies might coincide such as the placement+output from one might get nulled from the placement+output of another. So it is possible one at a time might produce sound, but two together nulls out at one specific frequency. Hence measuring and adjusting each separately, then testing the complete system is very important to achieve good results.

These days I've resorted to the following routine:
Measure in at least 4 different locations per speaker/sub, look for only the most important things that stick out around the same frequency across all measurements, repeat process at the other speakers/subs, test, repeat until happy.

Quite often I find that to achieve consistent results it is better to iron out the problematic frequencies first, sometimes that can make everything in the same area a bit smoother.
When everything at all speakers/subs looks "good enough" it's time to adjust the general curve to taste.
 
I should learn not to ask rhetorical questions 🙂

The more subs there are averaged in the room, the less variation in response (or listening area power at least) there should be. This assumes adequate averaging which implies sufficient diversity and cooperation between sources.

A good setup might be at +/-6dB, which implies no nulls, and maybe as good as +/-3dB at which point EQ will take over.
 
Hmm set up many a small room with speakers in the corners with the LP at the opposite wall, just needed to get toe-in right and place decorative wall damping around the LP to quell any close by early reflections.

GM
 
It's an involved process, sure, but not to miss the point.. multiple subs and similar schemes offer more than just multi location listening. Besides, with single subs how easy is it to end up with a null to deal with?
I don't know anymore, it's been at least 14 years since the last time I had a single-sub system. Everything happens in stereo for me now.


Something that hasn't been mentioned, and the OP may not be aware of, but as far as I know, no matter what the speaker set up, you aren't going to get a smooth response sitting near a wall.

If by smooth you mean "flat" then I agree, not likely to happen.
It is very rare, but I have experienced an even low frequency boost by sitting close to a wall no peaks or dips, just a bit "more". On the couch in our livingroom.