John Curl's Blowtorch preamplifier part II

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We visited a sales tour / open house in Los Gatos (Silicon Valley hometown of Netflix) of a 4 bedroom home. Astonishingly, the ratio

(Asking Price) / (Square Footage)

was a tad more than $1200 per square foot. This was a 4 bedroom house on a half acre lot, with a pool. We didn't make an offer. Here's a photo.

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REALLY? That's interesting... Did this include eating the entire soy product, or isolated phytoestrogen? What carrier?

Isolated phytoestrogens using an MCF-7 cell culture, with direct measurement of proliferation versus negative and positive controls. The binding affinities of some of the phytoestrogens were surprisingly high.

If you're interested in the subject, Heather Patisaul did a superb review paper a few years ago. She does an excellent job of teasing out information beyond sweeping and overbroad conclusions, a model of good science.
The pros and cons of phytoestrogens
 
I'm amazed...someone asking ME technical questions?

🙂
Henry,
Is that locally sources bees wax, I wouldn't want that East Coast wax in my California power supply. 🙄

On a more audio related subject I have a question about using an ADAU1701 and a TI TPA3251D class-d chip. Would you place a balanced line driver between those two, the TPA seems to appreciate a balanced line drive on the input. I can't discern if the ADAU is balanced output or se, I have a feeling the analog outputs are single ended. I was looking at the THAT 1606 to take care of this if necessary.

If you ever read some of my serious posts you would quickly realize I don't know squat about electronics and if I tried giving an answer, and you followed it, you'd likely be electrocuted.

I'm sure someone, with real knowledge, will provide an answer soon. I'm just havin fun with the snake oil shitz.

Good Luck,
Henry
 
We visited a sales tour / open house in Los Gatos (Silicon Valley hometown of Netflix) of a 4 bedroom home. Astonishingly, the ratio

(Asking Price) / (Square Footage)

was a tad more than $1200 per square foot. This was a 4 bedroom house on a half acre lot, with a pool. We didn't make an offer. Here's a photo.

_
1A8Qb9o.jpg


Best thing I found was to work yourself into a work at home situation. and just come in for meetings and special occasions. Even my neighbor does this and goes to office 500 miles away once a month. Everything else is by computer/phone etc. Then you can live in any style home you like for a reasonable price. I have 2 acres and stretched out 3/4 bdrm house with heated pool and spa (indoors). Cheap compared to Bay Area --- I love it.

I have been asked to work in Bay Area but always refused because I would only be working for the mortgage/real estate industry and have nothing more left over for when ever I decide I am old.


-RNM
 
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On a more audio related subject I have a question about using an ADAU1701 and a TI TPA3251D class-d chip. Would you place a balanced line driver between those two, the TPA seems to appreciate a balanced line drive on the input. I can't discern if the ADAU is balanced output or se, I have a feeling the analog outputs are single ended. I was looking at the THAT 1606 to take care of this if necessary.
See page 21 of the ADAU datasheet. There are four single-ended outputs, each requiring a lowpass reconstruction filter. I'd suppose I would roll the differential outputs into the filters. They don't have to be as perfect as THAT parts. In fact the specs on the ADCs and DACs in the ADI part aren't all that great to begin with.
 
100K USD in Bay area is a minimum requirement just for showing up to work.

Less than 80-100K means a long commute from a reasonable living area.


-RNM

Yes, I know - I interviewed there for a job about 3 years ago (internal transfer from Asia at senior level on the business side). The figures I quoted were for UK - I should have made that clearer - apologies.

Very, very lucky it did not work out.

I was across there for meetings very often over the last 15 years or so.

California is beautiful, but its totally crazy.

No hard feelings.

🙂
 
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We visited a sales tour / open house in Los Gatos (Silicon Valley hometown of Netflix) of a 4 bedroom home. Astonishingly, the ratio

(Asking Price) / (Square Footage)

was a tad more than $1200 per square foot. This was a 4 bedroom house on a half acre lot, with a pool. We didn't make an offer.
A couple I know managed to buy a nice place in Los Gatos. One is a retired music professor and former department chair. His considerably younger husband works for Google and makes "the big bucks". They sold a place in Hollywood that I thought was very nice, but necessitated a frequent and long commute for Daniel, so when Roger was able to retire, the place was on the market and sold promptly, I don't know for how much. But enough for a big down I'm sure.
 
Thanks Brad. Without going the overkill route with my self powered speaker the ADAU1701 seemed a practical solution. I know ADI has more advanced chips but then they require many more external parts and circuits to make them work. I'm trying to be practical as I am sure you would be if you were aiming for a price point that wasn't in the audiophile realm. I could look at a Shark or one of the other ADAU chips with external dac and adc but there goes some serious circuit design. You were busy!
 
Thanks Brad. Without going the overkill route with my self powered speaker the ADAU1701 seemed a practical solution. I know ADI has more advanced chips but then they require many more external parts and circuits to make them work. I'm trying to be practical as I am sure you would be if you were aiming for a price point that wasn't in the audiophile realm. I could look at a Shark or one of the other ADAU chips with external dac and adc but there goes some serious circuit design. You were busy!
I suspect it will do just fine.
EDIT: And recall that balanced means equal impedances to common on each line, and does not require equal and opposite voltages or currents.
 
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Contrary to SY's natural knee-jerk bashing..... yes it was rats and it was a serious journal/researched. It was not a very complex question --- does animal or vegetable proteins have same/different or ?? on cancer tumor growth and if so at what protein levels of each. No amount of plant protein caused the tumor to grow.
My sister was a vegetarian and died of cancer. So guessing this was a particular type of cancer in a mouse that was GM to get cancer guaranteed or your money back. But begs the question if veg proteins didn't cause the cancer to grow how did it get there in the first place to a detectable level? Any bio types know?
BTW -- If you eat little or no animal derived foods (eggs, milk etc) then you might get deficient in essential B12 and supplementation would be in order. tests will tell you.


THx-RNMarsh
Twice you have confused vegetarians with vegans. I even posted you the scott pilgrim link to try and explain it 🙂. Those of us who eschew meaty stuff know about having to keep the balance right, luckily not hard as long as you like pulses. I couldn't be vegan, I like cheese too much.
 
The bay area is not as evil as some of you make it out to be. First off if you purchase a house around it you're making a huge investment. Yes on 80-100k you'll be living a tight budget, but if your wife also works it won't be as bad. After so many years you sell and buy a bigger better home, appreciation and payments will give you a sizeable down payment towards the next place. Hopefully over the years your pay increased some. Then when you eventually decide to retire you sell your home, and have a very nice nest egg. It's so big you can move somewhere else and build a new very large nice home on great property/move into inner city. That way you get to **** up someone else's economy/gentrification instead of letting SF screw you as your income goes down.
 
bcarso,
Yes the TPA3251D wants balanced input impedance. I'm not mixing that up with a fully balanced audio structure like pro-audio balanced gear, not expecting most people to use a balanced audio system. It seems from what I gather that the THD goes up on that monolithic amplifier if the input impedance isn't balanced.
 
My sister was a vegetarian and died of cancer. So guessing this was a particular type of cancer in a mouse that was GM to get cancer guaranteed or your money back. But begs the question if veg proteins didn't cause the cancer to grow how did it get there in the first place to a detectable level? Any bio types know?

Twice you have confused vegetarians with vegans. I even posted you the scott pilgrim link to try and explain it 🙂. Those of us who eschew meaty stuff know about having to keep the balance right, luckily not hard as long as you like pulses. I couldn't be vegan, I like cheese too much.

Hi, this isn't how cancer works.

First off Mr Bill, cancer doesn't "get in". Cancer is when a transcription of DNA (RNA is the intermediate version) gets incorrectly made. The new cell is likely to loose it's designation, but most importantly it does not have a programmed stopping point for replication. This means that the cell replicates endlessly. And hence a tumor grows.

What you also don't know is that cancer is common in all humans. The difference between you and your sister is that when say your prostate had a few cancer cells, your immune system dealt with it. With her it missed them or did not see them as a problem. Now obviously the more frequently we develop little cancers, the higher the likelihood is that our immune system misses something. Now also a problem is that there are factors that increase cancer growth possibilities.

Cancer tends to build and build as a tumor, eventually a piece breaks off and it flows about the body. Then it signals for new cells to be made. It appears from what we do know that where ever it stops/gets stuck, it starts to grow tumors there too. There's a lot of talk about the study of why and how it stops/gets stuck. For example we know AGE's (advanced glycogen endproducts) are a precursor to cancer, but it's not entirely clear if they help floating cells stick, if the cell they are on is more susceptible, or if its playing a role in mistranscitpion.

So you see how and why cancer is so complicated. We all pray for simple answers with it, but we don't have them. People with autoimmune disease get cancer, even though their immune system is very over-active. People who live with more viruses and bacteria, no allergies, etc, in a form of peaceful coexistence can have a depressed immune system and get cancer.

What we do know is some things that help. Antioxidents of specific types are useful because they help keep us clean of AGE's and other things that cause cellular problems. Now for some people their body generates a lot more antioxidents naturally, some less (although not specifically ones for AGE's). Very confusing because we also need the by-products of actions such as lifting weights, to help us build muscle, but antioxidents like to bind to these stress induced particulates. Perhaps part of the answer is to help regulate our production of free radicals/oxidative stressors etc.

However it's very clear out gut flora regulates the immune system. There for it's very advisable to have good gut flora. That's complicated too. I won't get into such a thing on the forum since it's a broad topic until you start to throw in specific people. But for example there's no guarantee a vegetarian diet was best for your sisters body. Some people can't seem to have good digestion without some meat. There's some pretty clear lines in the sand showing a likely reason why we are so different on that. But a lack of studies showing using that knowledge has led everyone to believe it's all fluff.
 
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My sister was a microbiologist so I do know a few things I picked up from her. So saying 'you don't know' in response to a gentle rib to Mr Marsh is a bit of a knee jerk. I had long conversations with my sister about this. The fact that we are only 10% Eukaryotic cells and in fact despite thinking ourselves as single organisms are in fact walking digesters feeding all the hangers on, who have evolved some very complex symbiotic relationships with us is not lost.

Of course being a microbiologist she had to get a cancer so rare that there was no accepted treatment path. I suspect at least one person will use a lump of her to get their PhD. She would have liked that....

I am fascinated by the adaptations of certain populations to particular diets. For example Inuit who never eat veg at all and some native American tribes. I wish I had more time to study the research. What is sure is that, since 1953 and watson and crick, we have learned that we still don't understand how humans actually hold together for 70 years. But its a sure bet that in the future the doctors will be delivering a lot more enemas!

But I still don't know how the mice got cancer of a detectable size if on a veg diet that didn't grow the cancer. As you well know, by the time a cancer is detectable its had a fair few generations to grow.
 
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