DC-DC Converter (Switch or linear) Help (Lowest Noise Possible)

Hey there everyone!

New to electronics in general, but need help with an issue I'm facing for a personal project. Anything that could help would be much appreciated!

I'm trying to design a circuit that boosts DC to DC cleanly in the power section for an audio preamp I'm working on (500 series).

The preamp portion of the circuit is sort of plug and play as I've used it on other designs but the power section is what is hindering me from continuing on!

Now, I'm wanting to start with a +/-16vdc input in the actual real world application. (Variable input of something like 12-24v would be even better here!)

I need the output to be able to achieve a steady 400vdc or as steady as it can be. (Variable output up to 450v, 500v would be awesome too!) (CCM maybe?) (I don't know what I don't know)

The current doesn't matter much to me. Maybe like 5-20ma in the 400v range roughly.

Should I go with a boost converter? Flyback Converter? Do I use a high frequency transformer? Etc.

The only stipulations to my idea are:

not a ton of space to work with (500 series PCB for power and preamp circuits on final design).

I need it to be the cleanest output at 400v as I can get (minimize ripples).

Even if just providing schematics and parts that work on paper I can do all real world testing and man hours myself.

If you could work with me in anyway with a schematic and some parts that could be used for this, it would be so very much appreciated!

I've been all over asking for advice to no avail.

Thank you all, I hope we can all work on this :)
 
Well, if you want to avoid the switching noise of SMPS then there is always the old fashioned way which is rather inefficient. Basically, you make a sine wave oscillator and power amp that you then step up through a power transformer to whatever voltage you need. Then you rectify it, filter it, and regulate as needed. At least you aren't restriced to 60Hz or whatever, so you reduced filtering needs by upping the frequency some. Or, if you don't need that much load current, you could use an oscillator and a Cockcoft-Walton Voltage multiplier: https://circuitcellar.com/resources/quickbits/cockcroft-walton-voltage-multiplier-2/ You may see that sometimes used in preamps that want a little tube distortion/sound for some reason or other.

OTOH, if you don't mind the very real risk of SMPS EMI/RFI noise getting into the rest of your circuit and intermodulating with your audio, then you can do whatever you want with any circuit you can think of.
 
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