Amplifier Single End vs Dual End - What does this really mean?

How does it (SE vs Push-Pull) affect the sound, if at all?
Does it make any difference?
It has major sound repercussions. As many designers will address the weaknesses of each configuration you will be less able to hear that sound effect on the driver , but if you switch amplifiers types you will be able to hear a great difference in the way music is presented. It is a matter of matching the right amp with right speakers.

With class d amps high power low cost great sound, theses amplifiers are going to be history, like vinyl.
 
With class d amps high power low cost great sound, theses amplifiers are going to be history, like vinyl.
There is room for every format and design, we're all different. I abandoned vinyl many years ago and deeply regret it now, despite having a significant Roon library of bit perfect flacc files and a few very nice DACs, like some people have different cartridges. I miss the process of thinking about which album to play, taking it out and starting the turntable, placing the arm gently on the plastic and then turning up the volume to hear the warm, immediate, vibrant and life like voices of the artists and their instruments. I often wonder what it would be like to hear artists like Clare Teal, Oscar Peterson, Anne Bisson, Suzanne Vega and especially the likes of Renaud Garcia-Fons on a really nice Linn LP12.

Instead I start Roon, choose the endpoint, maybe my Chord Qutest in my office, then choose a track and press play. It's very quick and easy and the sound is detailed and accurate. If I get bored I click a few times and something else appears in the room. I might change to the Denafrips DAC. It's too easy, plus the amp and speakers become more important as they need to reproduce the musicality and vibrancy missing from the digital reproduction. The Chord is way better than most DACs but having heard friend's analogue systems, it's a fantastic DAC but a pretty poor second to a good turntable setup, when it comes to making music come alive.