John Curl's Blowtorch preamplifier part II

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OMG! I don’t know if we will have a chance to meet in the future.:D What’s in your list, I did (do) exactly the opposite :usd:

George

George, all it requires is a little care and paying attention for the first 10-14 days, after that it becomes a habit. Hardly a difficult chore. I used to think it was torture, but discovered I was dead wrong.

Compared to the time, pain and learning you obviously invested in phono playback process, there's no way you'll ever convince anyone here that you can't do it. You just have to want to do it.
 
Cooking with olive oil , unless you talking about Popeye 's girlfriend i would watch that..:)

That's true. When heated up, olive oil satarts to change to change in properties and from highly desirable becomes not so desirable.

By the way best thing anyone can do is excercise , min 20 mins aerobic activity per day ...

Especially with hearty assistence from a female ... :D
 
I surely didn't say I was using olive oil to deep fry some twinkies! I know not to use it at high temperatures.

Good for you, but perhaps somebody else doesn't know.

On the other hand, fabulous for salads.

Did you know that in the Mediterranean region most are used to drinking a small glass (say 50 cc) of pure olive oil on a daily basis?

With a combination of wine drinking, also widespread, that region has one of the lowest stomach and heart ailment statistics in the world. That simply CAN'T be a coincidence, although I should also mention that their main meat consumption is related to sea food of course.
 
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one of the oleic acids we need to do well (meaning not vital, but highly recommended) can ONLY be found in pork.

You just shed light onto one of the mysteries of my life.
My wife (a pharmacologist ), refuses to divorce me although she calls me ‘pig


and hospitality is still a God's commandment.
Amen :xfingers:



George, all it requires is a little care

That’s true and thank you. All the burdens accumulated from my careless life will set me straight in the end.


Compared to the time, pain and learning you obviously

Pain? What pain? I never felt pain in my involvement with phono (till I met SY)

George
 
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You just shed light onto one of the mysteries of my life.
My wife (a pharmacologist ), refuses to divorce me although she calls me ‘pig

Just the sweet little nothing people in love tend to say. :D


That’s true and thank you. All the burdens accumulated from my careless life will set me straight in the end.

I once read somewhere that we spend the first 40 years living it out and the next 40 years paying for the first 40 years. :D


Pain? What pain? I never felt pain in my involvement with phono (till I met SY)

George

There you go, every family has its own black sheep - or buffalo. :p

I also thought I had most of it all figured out until Thorsten (not here) and Demian (supposed to be here but he ain't?) brought my feet back down onto the ground. All I can say is thank God I know them both, negative feedback can be a life saver if properly applied.
 
I didn't know that. Always use half butter half olive oil for frying meet. Do you know which dangerous compounds are created in olive oil by this? And which oil should I use instead to avoid it?

I don't remember the explanation of exactly what happens, but the point is that when heated hard, olive oil changes (modifies) its structural formula. Cooking with it is definitely not recommended.

Same goes for butter, much as I love frying my eggs on it.

In terms of heating up, sunflower seed based oil changes the least.

And there are some nasty surprises. A while ago, I threw a slice of Old Dutch Master Amsteram cheese over a steak I just turned over. I love that cheese and have it in my fridge almost always. I got a nasty shock when I saw it melt and deposit an unbelievable amount of fat. Only when I looked at the manufacturer's lable did I notice that fat content is (gulp!) 42%!

So, cold it's a delight to use, but heated up it's the last thing I'd recommend.
 
By the way best thing anyone can do is excercise , min 20 mins aerobic activity per day ...

Unfortunately, it seems that any exercise I do nowadays is anerobic.:eek:

My doc figures my peak heartrate at 140bpm, target should be 120 based on that equation. I told him 140bpm is about 30 seconds into a run, I can do 140 just by thinkin bout it..

He said...boy, that should make the workout easy, no?:D

I like to get my pulse up to about 175 bpm for 30 min, peak it at 185. Really feels good when I stop...


jn
 
Butter is saturated fat, it should be more stable as opposed to plant fats which are mostly unstable and rancidify quickly during cooking. Lard and tallow are extremely stable in heat, very nice to cook with. Antioxidants from spices such as Oregano or Rosemary or Bay Leaf can be used in cooking to stall the degeneration of fats - it sure helps with fried chicken where polyunsaturated fats go rancid easily.

Eating fat can't make you fat. The fat in stored in your cells is POA (palmitoleic acid), the body makes it itself from carbs, and it isn't chicken fat or beef fat or olive oil. Fat can't be converted to carbs or POA either. For those that have injured fat metabolism, it will just go right on through the body; for others the body will use a limited amount of saturated fat as fuel if they still get most of their energy from carbs. On the other hand the cell membranes in your body are made of whatever acceptable fats are available (especially cholesterol), and your brain itself is made of fat, so to restrict healthy fats is flirting with biological degeneration.

There is usually no need to eat more good-quality protein than your body requires for it's structure and neurotransmitters. A ballpark figure for this value is 0.8g-1g protein (which is carried in different proportions in different meats) per Kg of body weight per day. More meat than necessary stimulates the mTOR pathway (Ron Rosedale) which is helpful for bodybuilding but for longevity purposes isn't helpful.

Many people have a hard time maintaining muscle because at night, when the body fasts for however long it is asleep, it runs out of carbs. Without being ready to metabolize fat, it resorts to the liver to convert protein to carbs (gluconeogenesis) which is a suboptimal process with waste products and stresses the liver. If the body doesn't have plenty of protein during this time, it will cannibalize it's own protein instead (coming from the bones, teeth, organs, muscles). You can lose almost half a pound of lean protein in a single night this way. This continual breakdown and rebuilding reduces tissue quality.

For those that need to eat excess protein to preserve their muscle mass and neurotransmitters, stimulating the mTOR pathway is a necessity, so already one path to longevity is closed.

So good quality fats, of which animal fats are the majority, and a working fat metabolism are quite important for someone who wants to thrive for a significant fraction of their lifetime, for those of us with the usual genetics.
 
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In our family the long term olive oil average consumption is ~25lt per year per person. We use no other fat in the kitchen, even for frying, which we do not do frequently
Years ago I read some research papers suggesting olive oil is appropriate for frying and much healthier than using any saturated fats.
If you guys have confirmed evidence that this is unhealthy, drop me a message and I’ll kill my wife (but I’ll let my mother live).
With any kind of cooking, we do not raise the temperature above ~200-210 d C
Olive oil - Wikipedia, the free encyclopedia
Deep frying - Wikipedia, the free encyclopedia
Myths about olive oil | Fox News

I once read somewhere that we spend the first 40 years living it out and the next 40 years paying for the first 40 years. :D

Well, I was spending for a bit more than 40 years and no, I won’t be paying for 40 years. It’s too long


There you go, every family has its own black sheep - or buffalo. :p

I would say a ram.
But a predictable one.
As long as you have not partied with logic and experiment, SY is not going to hurt you.

Thorsten (not here) and Demian (supposed to be here but he ain't?)

I miss Thorsten.
I enjoy Demian.
And may I ask where is Brad?

brought my feet back down onto the ground
Strange, I don’t fancy flying (do elephants fly?)

negative feedback can be a life saver if properly applied.

That’s the reality check, yes?


Sounds crazy that high

I’ve heard the formula for max beat rate is “200 minus the individual’s age”

George
 
Sounds crazy that high , i usually see 160 as max sustained 145 for most of the 30 mins.
I know. Apparently, everybody is different. My doc used that formula as well.

When I started using a heart rate monitor, the numbers were startling. I spent about 2 weeks debugging the strap/watch set with a stopwatch and counting pulse, so I know it was reading right. A stress test also confirmed it.

I'll never forget the doc at that test. "Let us know when you can't go any longer".

When I could not go any longer (sustained 185), I said so...they then injected the contrast then said "go another minute".

WHAT part of the phrase "can't go any longer" did they not understand???:eek: As a former runner, the plan was always to synchronize "can't go any longer" with AT THE FINISH LINE.. (sometimes that plan worked...sometimes it didn't)

jn
 
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mTOR pathway

Recommended name:Serine/threonine-protein kinase mTOR
Function:
Serine/threonine protein kinase which is a central regulator of cellular metabolism, growth and survival in response to hormones, growth factors, nutrients, energy and stress signals. MTOR directly or indirectly regulates the phosphorylation of at least 800 proteins. Functions as part of 2 structurally and functionally distinct signaling complexes mTORC1 and mTORC2 (mTOR complex 1 and 2). Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. This includes phosphorylation of EIF4EBP1 and release of its inhibition toward the elongation initiation factor 4E (eiF4E). Moreover, phosphorylates and activates RPS6KB1 and RPS6KB2 that promote protein synthesis by modulating the activity of their downstream targets including ribosomal protein S6, eukaryotic translation initiation factor EIF4B, and the inhibitor of translation initiation PDCD4. Stimulates the pyrimidine biosynthesis pathway, both by acute regulation through RPS6KB1-mediated phosphorylation of the biosynthetic enzyme CAD, and delayed regulation, through transcriptional enhancement of the pentose phosphate pathway which produces 5-phosphoribosyl-1-pyrophosphate (PRPP), an allosteric activator of CAD at a later step in synthesis, this function is dependent on the mTORC1 complex. Regulates ribosome synthesis by activating RNA polymerase III-dependent transcription through phosphorylation and inhibition of MAF1 an RNA polymerase III-repressor. In parallel to protein synthesis, also regulates lipid synthesis through SREBF1/SREBP1 and LPIN1. To maintain energy homeostasis mTORC1 may also regulate mitochondrial biogenesis through regulation of PPARGC1A. mTORC1 also negatively regulates autophagy through phosphorylation of ULK1. Under nutrient sufficiency, phosphorylates ULK1 at 'Ser-758', disrupting the interaction with AMPK and preventing activation of ULK1. Also prevents autophagy through phosphorylation of the autophagy inhibitor DAP. mTORC1 exerts a feedback control on upstream growth factor signaling that includes phosphorylation and activation of GRB10 a INSR-dependent signaling suppressor. Among other potential targets mTORC1 may phosphorylate CLIP1 and regulate microtubules. As part of the mTORC2 complex MTOR may regulate other cellular processes including survival and organization of the cytoskeleton. Plays a critical role in the phosphorylation at 'Ser-473' of AKT1, a pro-survival effector of phosphoinositide 3-kinase, facilitating its activation by PDK1. mTORC2 may regulate the actin cytoskeleton, through phosphorylation of PRKCA, PXN and activation of the Rho-type guanine nucleotide exchange factors RHOA and RAC1A or RAC1B. mTORC2 also regulates the phosphorylation of SGK1 at 'Ser-422'.

OK
How many feedback loops do you spot there?

George
 
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Butter is saturated fat, it should be more stable as opposed to plant fats which are mostly unstable and rancidify quickly during cooking. Lard and tallow are extremely stable in heat, very nice to cook with. Antioxidants from spices such as Oregano or Rosemary or Bay Leaf can be used in cooking to stall the degeneration of fats - it sure helps with fried chicken where polyunsaturated fats go rancid easily.

Eating fat can't make you fat. The fat in stored in your cells is POA (palmitoleic acid), the body makes it itself from carbs, and it isn't chicken fat or beef fat or olive oil. Fat can't be converted to carbs or POA either. For those that have injured fat metabolism, it will just go right on through the body; for others the body will use a limited amount of saturated fat as fuel if they still get most of their energy from carbs. On the other hand the cell membranes in your body are made of whatever acceptable fats are available (especially cholesterol), and your brain itself is made of fat, so to restrict healthy fats is flirting with biological degeneration.

There is usually no need to eat more good-quality protein than your body requires for it's structure and neurotransmitters. A ballpark figure for this value is 0.8g-1g protein (which is carried in different proportions in different meats) per Kg of body weight per day. More meat than necessary stimulates the mTOR pathway (Ron Rosedale) which is helpful for bodybuilding but for longevity purposes isn't helpful.

Many people have a hard time maintaining muscle because at night, when the body fasts for however long it is asleep, it runs out of carbs. Without being ready to metabolize fat, it resorts to the liver to convert protein to carbs (gluconeogenesis) which is a suboptimal process with waste products and stresses the liver. If the body doesn't have plenty of protein during this time, it will cannibalize it's own protein instead (coming from the bones, teeth, organs, muscles). You can lose almost half a pound of lean protein in a single night this way. This continual breakdown and rebuilding reduces tissue quality.

For those that need to eat excess protein to preserve their muscle mass and neurotransmitters, stimulating the mTOR pathway is a necessity, so already one path to longevity is closed.

So good quality fats, of which animal fats are the majority, and a working fat metabolism are quite important for someone who wants to thrive for a significant fraction of their lifetime, for those of us with the usual genetics.


Does limiting fats in diet cause the body to produce more cholesterol?

-RM
 
Does limiting fats in diet cause the body to produce more cholesterol?

-RM

If you stop eating cholesterol, your liver will begin to manufacture it. This is more stress than if you simply ate the cholesterol instead and left your liver to do other important things.

Cholesterol is necessary. The problem is oxidized cholesterol, which is a sign of stress elsewhere in the body.
 
JN
When I was younger, much younger now I was doing a normal doctors visit when he noticed a murmur. I never had anything like that before so it got the doctors attention. Of course that meant a 24 hour EKG monitor and then on to the stress test. I was a swimmer and bicycle rider and was in great shape. They put me on the that running machine and slowly increased the tilt angle until it wouldn't go any higher. After I don't know how long they said stop. we have never had anyone last this long on the test and nothing look wrong. Turned out as soon as my heart was under any stress the murmur disappeared completely. I had a funny feeling about what had happened and it was confirmed by a doctor who was involved in tropical diseases, I had picked up a parasite from some dirty water in the back country in Hawaii that was making this happen. Eventually the murmur disappeared, never shows up anymore, it was some nasty little bugger messing with the heart. I learned a lesson about never trusting rushing water from an unknown source. Got a water purifier after that one experience.

dvv,
Can't believe that in Europe that you would have anything called American Cheese! I surely don't call what we have here in the US as American cheese real cheese. That is processed fat and some milk solids added to make some stuff to go on burgers and such. No way is it a cheese in the traditional sense, I don't have that around my house. With all the great cheeses you have there why you would eat that is beyond me! I prefer something that says sharp or extra sharp or most any cheese that has been aged for the longer the better, not something that was made overnight!
 
I hate to depart from the present topic. I have to go to the doctor, myself, today.
However, all else being equal, a higher voltage dual power supply is better than a lower voltage one. We usually start with +/- 30V from a remote location and step it down slightly with a final power supply buffer on each stage.
 
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