I would not, it is a stereo amp after all. There are two power amps, each expecting their own current feedback. When chorus is off, the signal is th same to both sides, so a single speaker strung between channels would produce...nothing.
I am a rank novice, but given the diagram above I couldn’t think of a way to do it. I need to find some better 8” speakers. ��. This amp sounds awesome when I hook it up to 2 10”s but they won’t fit in the cab.