New Project - Underbed Sub Mk IV

Apparently, I rocked someone's world in the wrong way. I was made an offer I couldn't refuse for my MK III under-bed sub.
A MK IV design is afoot.
I'm going for a ported design.
Maximum driver size is 6.5"
Cabinet volume is 46 litres.
I err on the side of efficiency.
Where should I start looking? 4 x 5" or 2 x 6.5"?