TPA3251d2

Quite possibly, yeah.

If the L is changing with the audio envelope, it causes the output filter Fc and Q to move around with the L, causing the high frequency response of the filter to dynamically change.

It isn't a huge stretch to imagine low frequency content effectively causing AM/PM modulation of high frequency content, causing IM distortion.
 
Like so.. :snoopy:
 

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I think there will be quite a difference between Inductors using ferrite and those using some kind of iron powder like carbonyl. Compare the L vs current diagrams and you will see the difference. Ferrite shows a sharp saturation point, iron powder degenerates in a more smooth way. Actually I compare 10uH smd inductors in a stepup converter (3 amps ripple current at 250kHz) and found that carbonyl cores are less lossy than their ferrite counterparts.
 
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So we have

carbonyl = soft saturation, less loss
ferrite = hard saturation, more loss

?

For the comparsion, lin vs log makes the "difference".

All 10uH inductors
Coilcraft HA3588-BL = AGP2923-103KL = VER2923-103KL
Coilcraft MA5172-AE - stated as 10uH, from the datasheet
Bourns SRP1245A

While Coilcraft prefers dual-log, Bourns do dual-lin.
 

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Well, my design's coming along. Nothing's committed to PCB yet, but I've got the schematic mostly put together. Some design notes:

Card can be powered off a single 24-36V supply. I'm using a LM25017 buck regulator IC to make 12V from the input voltage to power VDD/GVDD and the analog input stage, and a secondary winding on the buck inductor makes -12V for the analog input.

Analog input is a pair of instrumentation amplifiers made out of OPA2134s, providing "proper" differential inputs that'll behave nicely with both single-ended and differential input sources. There'll be jumpers or DIP switches to set the input gain. There'll be good input protection using diodes to clamp the inputs to protection rails.

I'll have a microcontroller handling startup/shutdown. I'll provide drive for a bicolor red/green LED displaying different states. LED off = amp off, green = amp running, amber = overtemperature warning, red = bad things.

Still figuring out heatsinking. Original plan was to mount the TPA bottom-side and bolt the card to a metal plate, but instead I'll mount the TPA topside with a bolt-on heatsink, and mount the small decoupling bottom-side instead so I can have it in close proximity to the TPA. Getting metal plates made in low quantities is way too expensive in low quantities, and the costs of screws/standoffs/etc adds up pretty quick too.
 
Bottom side decoupling for everything on PVCC won't be a good thing in my opinion. The Tpa is 1mm in height so caps will fit if you split the decoupling. Have a look for 0612 TDK low profile.
I'll fit whatever I can under the heatsink. The bigger 0805/1210 caps I use on PVCC/AVCC/etc will have to go bottom side, I don't think it's a huge issue.

Opening up the bottom side for parts will probably also help with things like decoupling the audio input op-amps while maintaining a tight/clean layout.

We'll see, haven't begin PCB work yet.