As BigUn suggests, with the right speaker…
A typical SE amp has a higher output imedance which means that the speaker impedance, to some extent, is imposed on the FR.
This often leads to the bass & treble changes suggestted by stocktrade, often works well to extend teh response, happens because we typically have an impedance rise at impedance and often in the top. This kind of speaker impedance is most often seen in single FR speakers. Multiways all to often have a big midrange impedance peak due to the XO that directly affects that region.
No crossover distortion — SE is always Class A, and in a tube SE amp, unless parafeed, the transformer goes not have a zero crossing in the transfer curve of the OPT. So at low levels they tend to be more seemless.
The nature of SE means a distortion spectra with diminishing amounts as the order increases. Predominantly 2nd order, with assymetrical clipping. In a PP amp the 2nd harmonic mostly cancels out as do other even order harmonic products. A PP typically has much lower numbers, but the ear/brain finds the continually decreasing harmonic producs with order sounds more natural and anything over 3 is not something we hear often in nature so adds information tha is unnatural.
At this point i would like to nite that this is not fixed in stone, a few PP amps, like the AKSAs, have been fine tuned to have a distortion profile closer to typical SE. Mine is still parts but they are highly respected amplifiers.
Human perception of these kinds of things can be significantly different, as well as a huge range of implementation, means you have to try and se ewhat works for you
dave