That design is far from elegant. Can you offer some insight into what you expect from this circuit, the rationale for this circuit topology (especially the voltage doubler input section), and your selection of component values.
Before you design a PC board you generally have at least a rough idea of what space the board must fit into, what the input and output connection interfaces are, and whether it'll be surface mount or through hole. In this particular case I'd want to have more info about that transformer!
> IEPE (ICP®) Sensors
These do not eat 24V directly! You feed them with a constant current source of 4mA or 20mA, limited to 24V max. The signal is current-mode.