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Old 19th March 2013, 01:44 AM   #131
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Quote:
Originally Posted by Bill poster View Post
a subject that is close to home, currently nursing my father - interestingly he wasnt allowed any supplements during treatment, lycopene etc. But diet wise, I went military with his food, as well as lots of fish and other things I introduced a mix of asian mushroom varieties, such as Shiitake, Maitake and Enoki, which i believe does make a difference.

Get well soon.
Thanks Bill, (guys),
I'm pretty much following your farther's approach. Haven't eaten any meat (red or white) since mid Jan, just fish, veggies, fruits etc etc. I feel better for the change.
Cheers
Mark.
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Old 19th March 2013, 02:22 AM   #132
JMFahey is offline JMFahey  Argentina
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Dear Markaudio, with the utmost respect, may I suggest you follow to the point whatever your "main" Doctors (the ones who operated you) say you need, including chemo/Radiation, or anything they find will work.
Workout, diet change, alternative treatments, etc. have their value, but they must *not* unfocus you from your main treatment.
And if you go "Doctor shopping" you will unfocus even more, bacause around this terrible problem there are as many opinions as there are Doctors.
What happened to the original Team Oncologist?
Did he suggest Xeloda or did you get the idea from somebody else?
Or reading online?
Best wishes
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Old 19th March 2013, 03:27 AM   #133
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Quote:
Originally Posted by JMFahey View Post
Dear Markaudio, with the utmost respect, may I suggest you follow to the point whatever your "main" Doctors (the ones who operated you) say you need, including chemo/Radiation, or anything they find will work.
Workout, diet change, alternative treatments, etc. have their value, but they must *not* unfocus you from your main treatment.
And if you go "Doctor shopping" you will unfocus even more, bacause around this terrible problem there are as many opinions as there are Doctors.
What happened to the original Team Oncologist?
Did he suggest Xeloda or did you get the idea from somebody else?
Or reading online?
Best wishes
Hi JM,
Thanks for your good intentions but you've made errors in your analysis and observations.

The time-line for my critical (life threatening) condition (blocked colon) had to be surgical intervention first. Therefore, the "main team" as you put it were surgical, not oncological.

Pathology from the operative sample showed I'm an earlier stage 2 (Dukes T3N0) colon cancer survivor with a single site tumour and no detectable metastasis.

Given my analytical method based nature, I have VERY carefully researched the outcomes from my Descending Hemicolectomy surgery and the potential for post operative treatment. I'm more than well briefed on the Xeloda and other chemo interventions.

I certainly am "doctor shopping" as you describe it, since there is no medical consensus on post operative treatment for early stage 2 colon cancer, nor are the outcomes for this class of drugs proven to be reliable. The side effects range from mild to being harmful. There is a large body of reasonably credible evidence showing that relapse rates can be minimised by improvements in post-operative fitness and optimised diet. Therefore the different approaches to post operative treatment have to be VERY carefully evaluated:

1 - What is the "actual" net effectiveness gain (years of life saved/extended/survived) when using Xeloda in a early stage colon cancer condition? Where is the research to demonstrate this gain? Is such research reliable - i.e, has a control (placebo) and a treated group of sufficient sample size for the validation of its outcomes?

2 - What body of evidence exits to demonstrate increased levels of post-operative fitness and improved diet can reduced relapse and increase survival rates? What are the net gains?

3 - Could Xeloda dosage volumes be "managed" to minimise its side effects, sufficient to retain the fitness program while maintaing its clinical effectiveness? What would be the total survival net gain?

All these questions are taking allot of my time (too much as I'd like to get on with designing and making drivers). If you really want to help, do some quality review/research for me, the information you need is above. I'd value this help more rather than second guessing my ability to manage my condition.

My focus remains LASER sharp!

Mark

Last edited by markaudio; 19th March 2013 at 04:28 AM.
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Old 19th March 2013, 04:37 AM   #134
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On the subject of second guessing, I would have thought, Mark, that the accumulated experience of a qualified practitioner would count for something.

I've seen a lot of guys here with 5 minutes accumulated knowledge of electronics make damn fools of themselves trying to second guess guys who have been doing this stuff all their lives. Many of them are trying to find justification for preconceived ideas.

I for one wouldn't be asking forum or other acquaintances to do review/research for me when I could draw on the accumulated experience of experts in the field.

Outcomes may in any case be dependent on the quality of care with which the treatment plan is executed, so raw statistics may not tell the whole story.

Far be it from me in most circumstances to discourage or undermine the confidence of anyone taking responsibility for their own treatment, but are you sure you're not just looking for reasons to dodge the chemo, or even, given an earlier remark you made, reasons not to pay for it?

Good luck.
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Old 19th March 2013, 08:55 AM   #135
JMFahey is offline JMFahey  Argentina
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Dear MarkAudio, I wish you the best, and trust the outcome will be good.
All I can say is trust your Doctors.
Good luck and best wishes.
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Old 19th March 2013, 12:45 PM   #136
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Originally Posted by counter culture View Post
On the subject of second guessing,

1 - I would have thought, Mark, that the accumulated experience of a qualified practitioner would count for something.

2 - I've seen a lot of guys here with 5 minutes accumulated knowledge of electronics make damn fools of themselves trying to second guess guys who have been doing this stuff all their lives. Many of them are trying to find justification for preconceived ideas.

3 - I for one wouldn't be asking forum or other acquaintances to do review/research for me when I could draw on the accumulated experience of experts in the field.

4 - Outcomes may in any case be dependent on the quality of care with which the treatment plan is executed, so raw statistics may not tell the whole story.

5 - Far be it from me in most circumstances to discourage or undermine the confidence of anyone taking responsibility for their own treatment, but are you sure you're not just looking for reasons to dodge the chemo, or even, given an earlier remark you made, reasons not to pay for it?

Good luck.
Hi Counter,
I've numbered your response to make it easier.

1 - I doubt that a single practitioner would/could claim to have so much experience as to exclude follow alternative professional thinking. Fundamental facts are being skated over in yours and member FW's line of thinking. There is No consensus from professional oncological specialists, or associated medical researchers on the issue of the effective application of Xeloda for cancer survivors in my stage condition. I'm finding significant variation (3 oncologists contacted so far) in oncological responses to my condition. Therefore relying in a single professional opinion in my case is Not wise.

2 - I've some sympathy with this comment. There are times when I've had to apply allot of self restraint over the last few years, as a rare few members took it upon themselves to "lecture" me on the design of drivers, they having never designed or built a driver in their lives. However, I'm certainly not "lecturing" medical professionals and find the implied nature of your comment disturbing. I am asking serious reasoned questions as to the potential and effectiveness of a post operative intervention thats being offered, a very sensible thing to do given my prognosis. The medical professions don't have all the answers and aren't complete fountains of knowledge.

3 - I've received fantastic practical help and advice from several Diyaudio members, some of whom are long term cancer survivors. I won't ignore their experiences as they are just as valuable and insightful as any professional advice. My particular thanks to member EUVL, who's put me in contact with a Hong Kong physician who giving me excellent support through his fellow contacts. I certainly have no intention of throwing sand in the faces of these members who've given me their support. Nor will I turn away members who wish to help me.

4 - Agree with you on this point. Raw Stats aren't that focused but they point in a direction that helps me make a informed decision.

5 - I came close to editing out your last comment. I'm not sure of your intension but its somewhat insulting of my powers of assessment and reasoning. If Xeloda can clearly demonstrate that it can authentically assist in the improvement of my prognosis without causing harm, I'll take it. I'm not a bloody fool!

Mark.

Last edited by markaudio; 19th March 2013 at 01:36 PM.
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Old 19th March 2013, 12:55 PM   #137
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Originally Posted by JMFahey View Post
Dear MarkAudio, I wish you the best, and trust the outcome will be good.
All I can say is trust your Doctors.
Good luck and best wishes.
Hi JM, I appreciate your good wishes and support.

I find it disheartening that you've completely skated over the medical complexity of my situation, ignoring the lack of medical agreement/consensus and the subsequent stress it creates for people in my situation. Simply saying "trust your doctors" when they don't agree and don't have the answers just adds stress.

Thankfully, the many posts offering good wishes, support, encouraging me to keep going help a great deal.

Thanks
Mark.
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Old 19th March 2013, 01:24 PM   #138
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Without trying to sound patronizing, Mark is a pretty smart guy. He'll sort through the options and do what is best for him.

The best thing we can do is support him through the more trying parts of his follow-up treatment.

All the best wishes and prayers for a speedy and complete recovery,

Bill
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Old 19th March 2013, 10:09 PM   #139
bocosb is online now bocosb  Romania
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Hello Mark just wanted to say i am a big fan of your work, i have a pair of Alpair 7.3 burning in at the moment, waiting for the enclosures to be ready and i have to say that i am amazed at the sound, details and musicality these drivers are capable of.
On topic, i have a site i usually check when i have questions about medical stuff. It's mainly a database of clinical trials, studies and articles on almost everything related to the medical field. Home - PubMed - NCBI
Hope this helps and i'm confident you will find the best direction to follow.

I post a picture with the cardboard boxes i made for burn in i'm really happy with the sound even in these (and even at the low volumes).
Best regards,
Benny
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Old 19th March 2013, 11:24 PM   #140
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Mark,
I have lost two family members to cancer. I do not say this to be grim, but to encourage you to be patient, diligent, as it sounds like you are doing. From what I have gathered you have very good prospects. I hope that your recovery continues to be successful and you find a doctor who fits. Strengthening your body with good food and good activities are as important as anything. Chemo and radiation are some of the most arcane practices left in the medical field, but in some cases they work. What path you take is wholly yours and no others and I wish you the best. I enjoy your drivers, but could care less about them, as they are nothing without the soul that created them.
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