New to Tube Amps/ Issues with Tube Amps

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Hey,

So I picked up a Crate Vintage Club 50w 2x12, and when the Overdrive Channel is active I normally had the Gain set to about 8-9 for nice sounding distortion. Last week when I brought the volume to just under 2 the amp started to give really bad (high pitched) feedback even with the guitar volume down all the way. I am very new to tube amp troubleshooting and this problem only occurs when the Overdrive Channel is active... Could this be a preamp tube issue/power tube issue or something else?
 
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